We’re delighted to announce that the 2020 Marie and Jack Shapiro Prize has been given to a study that looked at the safety and effectiveness of a potential drug for tinnitus.

The Shapiro Prize was presented virtually to Professor Deborah Hall (pictured) of NIHR Nottingham Biomedical Research Centre for the winning paper, which compared the novel drug AUT00063 with a placebo in a robust, statistically-powered, multi-centre randomised trial.

The prize was judged by our Professional Advisers’ Committee, who commented: “Although the end result was that it did not benefit people with tinnitus, this study represented a rigorous and innovative journey in medication development and testing, of a sort that is desperately needed in tinnitus in order to reach the ultimate goal of a cure.”

“On behalf of my co-authors, I'd like to say how pleased we are to receive this recognition from the British Tinnitus Association on the QUIET-1 trial. This work would not have been possible without the support of Professor Jaydip Ray, who was the trial's national Coordinating Investigator, the 18 investigational centres across the UK who enrolled all our patients, and to the Contract Research Organization and Independent Data Monitoring Committee who ensured that the trial was conducted according to regulatory standards. We hope that the learnings gained from this project may be of benefit to future research in tinnitus." Professor Hall

The study was sponsored by Autifony Therapeutics Limited and partly funded by an Innovate UK Biomedical Catalyst award.

We know that a drug for tinnitus would be warmly welcomed by the tinnitus community and this was one of the first robust randomised controlled trials for a potential pharmaceutical treatment.

This project was an important study and provides the tinnitus research community with many important learning points. These could provide essential information that will inform new research towards a cure.

Can you help?

Tinnitus research is dramatically underfunded and we’re committed to funding, supporting and lobbying for what’s needed to silence tinnitus once and for all. 

Please help us to fund important tinnitus research projects.

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