Information What can I do? Treatments Tinnitus and neuromodulation Name of treatment Neuromodulation (Acoustic CR neuromodulation) Type of treatment Physical device Claims for treatment Reduce tinnitus symptoms by desynchronization, anti-kindling, and change of abnormal frequency couplings. How treatment is delivered In-ear sound generation device Potential negative consequences Regarded as safe and well-tolerated.[1] Evidence offered: Papers available PubMed database has 20 papers with both ‘tinnitus’ and ‘neuromodulation’ in the title. Eight studies were included in a systematic review1. Conclusions drawn The available evidence is insufficient for clinical implementation of acoustic CR neuromodulation. A proof for the claim of desynchronization is still lacking.1 Quality of evidence[2] A Does the BTA recommend this treatment? No, until more high-quality evidence is available BTA opinion on this treatment: Independent evidence of the effectiveness of neuromodulation for tinnitus management is lacking. Would the BTA support further studies into this treatment? Yes, provided the study is of high quality. Verdict: Safety - is this treatment harmful? Regarded as safe Verdict: Efficacy - does this treatment work? No evidence of effectiveness [1] Wegger M, Ovesen T, Larsen DG. Acoustic Coordinated Reset Neuromodulation: A Systematic Review of a Novel Therapy for Tinnitus. Front Neurol. 2017;8:36. Published 2017 Feb 13. doi:10.3389/fneur.2017.00036 [2] A = Systematic review/meta analysis. B = Randomised control studies. C = Cohort studies. D = Case control studies. E = case studies/reports. +/- to be used to indicate quality within bands Download this information: Tinnitus_and_neuromodulation_April_2019.pdf Published 15 April 2019